How Vytamin D3 5000 with K2 Works
Vitamin D3 is structurally similar to cholesterol, and is converted via the liver and kidneys to its active form calcitriol. It is imperative that oral supplementation of Vitamin D come in the form of D3; this is the most bioavailable form of Vitamin D in a softgel, maximizing its absorption into the body. 2,3 Calcitriol goes on to perform a multitude of roles in the body, and is particularly crucial for proper absorption of the minerals calcium, iron, magnesium, phosphate and zinc. Calcitriol also supports and promotes bone growth as well as immune, cardiac, and neuromuscular functions.
It is crucial to obtain adequate amounts of Vitamin D on a daily basis, as deficiency can lead to a host of health issues.4,5
Vitamin K2 (menaquinone) comes in a variety of forms, with evidence suggesting that the form MK-7 is particularly important for people that have chronic health issues causing nutrient malabsorption.6 Research demonstrates that Vitamin K2 is a crucial micronutrient for supporting the cardiovascular system and bone health. 7,8
Vytamin D3 5000 with K2 Supplementation
Given the importance of adequate Vitamin D levels in the body and many people’s lack of exposure to direct sunlight, Vytamin D3 5000 with K2 supplementation can help users in a variety of ways. The most relevant research-backed benefits derived from consumption of Vitamin D3 and K2 include: 9,10
- Supports cardiovascular function
- Supports healthy mood and stress levels
- Supports bone and skin tissues
- Supports immune function
1. Omdahl, J. L., & DeLuca, H. F. (1973). Regulation of vitamin D metabolism and function. Physiological reviews, 53(2), 327-372.
2. Holick MF (March 2006). “High prevalence of vitamin D inadequacy and implications for health”. Mayo Clin. Proc. 81 (3): 353–73.
3. Armas LA, Hollis BW, Heaney RP (November 2004). “Vitamin D2 is much less effective than vitamin D3 in humans”. J. Clin. Endocrinol. Metab. 89 (11): 5387–91
4. Heaney RP (December 2004). “Functional indices of vitamin D status and ramifications of vitamin D deficiency”. The American Journal of Clinical Nutrition. 80 (6 Suppl): 1706S–9S
5. Holick MF (December 2004). “Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease”. The American Journal of Clinical Nutrition. 80 (6 Suppl): 1678S–88S
6. Westenfeld, R., Krueger, T., Schlieper, G., Cranenburg, E. C., Magdeleyns, E. J., Heidenreich, S., … & Floege, J. (2012). Effect of vitamin K2 supplementation on functional vitamin K deficiency in hemodialysis patients: a randomized trial. American Journal of Kidney Diseases, 59(2), 186- 195.
7. Plaza, S. M., & Lamson, D. W. (2005). Vitamin K2 in bone metabolism and osteoporosis. Alternative Medicine Review, 10(1).
8. El Asmar, M. S., Naoum, J. J., & Arbid, E. J. (2014). Vitamin K dependent proteins and the role of vitamin K2 in the modulation of vascular calcification: a review. Oman medical journal, 29(3), 172.
9. Vieth R (May 1999). “Vitamin D supplementation, 25-hydroxyvitamin D concentrations, and safety”. Am. J. Clin. Nutr. 69 (5): 842–56.
10. Chung M, Balk EM, Brendel M, Ip S, Lau J, Lee J, Lichtenstein A, Patel K, Raman G, Tatsioni A, Terasawa T, Trikalinos TA; Balk; Brendel; Ip; Lau; Lee; Lichtenstein; Patel; Raman; Tatsioni; Terasawa; Trikalinos (August 2009). “Vitamin D and calcium: a systematic review of health outcomes”. Evidence report/technology assessment (183): 1–420.