How Nyte Tyme Works
Clinical studies show that dietary intake of vitamin B6 is correlated with quality of sleep. Vitamin B6 must be obtained through diet and plays a critical role in the synthesis of neurotransmitters involved in the central nervous system and sleep patterns.
Furthermore, dietary intake of foods containing tryptophan also reveal their ability to support healthy sleep quality. Tryptophan is an essential amino acid and a precursor of serotonin, which also plays a critical role in supporting sleep onset due to its direct effect on GABAergic neurons. Serotonin is involved in many functions of the central nervous system including sleep.
Melatonin, a lipid soluble indolamine, is produced from serotonin in the pineal gland. It plays a role in sleep quality by signaling and reporting to cells about environmental factors leading to sleep such as the onset of night time. Melatonin also is a potent free radical scavenger.
L-Theanine also is a neurologically active amino acid that stimulates alpha brain waves creating a sense of deep relaxation. L-Theanine plays a role in the formation of GABA resulting in its ability to induce relaxation.
The herbal ingredients include hops, lemon balm, and valerian root known to possess relaxation affects due to their role as GABA receptors and support the central nervous system. The plant flavonoid compounds bind to receptors to promote deeper sleep.
Nyte Tyme Supplementation
The ingredients in Nyte Tyme are congruous with what research suggests to be effective and safe, particularly for promoting restful sleep.
Clinical evidence and research cited herein shows that the ingredients in Nyte Tyme may:
• Support decreased sleep onset time
• Promote healthy sleep quality
• Support mood
• Support free radical scavenging activity
1. Bent, S., Padula, A., Moore, D., Patterson, M., & Mehling, W. (2006). Valerian for sleep: A systematic review and meta-analysis. The American Journal of Medicine, 119(12), 1005-1012.
2. Gyllenhaal, C., Merritt, S. L., Peterson, S. D., Block, K. I., & Gochenour, T. (2000). Efficacy and safety of herbal stimulants and sedatives in sleep disorders. Sleep Medicine Reviews, 4(3), 229-251.
3. Peuhkuri, K., Sihvola, N., & Korpela, R. (2012). Diet promotes sleep duration and quality. Nutrition Research, 32(5), 309-319.
4. Fernstrand, P. L., & Garssen, J. (2015). The effect of dietary intake of vitamin B6 on sleep quality and insomnia. European Neuropsychopharmacology, 25(S2), 654.
5. Lieberman, H. R., Agarwal, S., & Fulgoni, V. L. (2016). Tryptophan intake in the US adult population is not related to liver or kidney function but is associated with depression and sleep outcomes. The Journal of Nutrition, 146(12), 2609S-2615S.
6. Bravo, R., Franco, L., Rodriguez, A. B., Ugartemendia, L., Barriga, C., & Cubero, J. (2018). Tryptophan and hops: Chrononutrition tools to improve sleep/wake circadian rythms. Annals of Clinical Nutrition, 1-7.
7. Heminger, B., & Sheridan, D. (2018). Could melatonin be the cure for sleepless nights? Nursing, 48(1), 69.
8. Mason, R. (2001). 200 mg of zen. Alternative and Complementary Therapies, 91-95.
9. Taavoni, S., Nazem Ekbatani, N., & Haghani, H. (2013). Valerian/lemon balm use for sleep disorders during menopause. Complementary Therapies in Clinical Practice, 19(4), 193-196.