How Burn & Shyne Works
The choline in Burn & Shyne promotes cellular membrane structure and healthy trans-membrane signaling.t1,2 Choline supports healthy fat metabolism through these cellular processes.t2 Choline also works in conjunction with inositol to metabolize fat. 2,3 Methionine is an essential amino acid needed to produce choline, and it supports taurine synthesis, another amino acid involved in healthy fat metabolism. 4,5
Burn & Shyne provides choleretic and cholagogue gastrointestinal agents. Choleretic agents increase the volume of bile produced by the liver to absorb dietary fats in the small intestine. Cholagogue agents promote the healthy flow of bile from the liver and gall bladder into the intestines and eventually, the bowel for excretion from the body.
The formula is complemented with several flavonoids to promote healthy cell-signaling and further support fat metabolism. 6,7,8,9,10 Artichoke extract and beetroot powder have choleretic and cholagogue properties. Dandelion root powder, tangerine extract, and gentian extract have cholagogue properties. All support healthy lipid oxidation and promote healthy inflammatory markers that positively impact fat accumulation in the liver. 6,7,8,9,10
Burn & Shyne Supplementation
The ingredients in Burn & Shyne are dosed in a manner that is congruous with what research suggests to be effective and safe, particularly for supporting healthy fat metabolism.
Clinical evidence and research cited herein show that the ingredients in Burn & Shyne may:
- Support healthy fat metabolism
- Promote healthy liver function
- Promote healthy bile processes
- Promote cellular efficiency
- Support cell membrane integrity
- Zeisel, S. H., & da Costa, K.-A. (2009). Choline: An essential nutrient for public health. Nutrition Reviews, 67(11), 615-623.
- Hongu, N., & Sachan, D. S. (2003). Carnitine and choline supplementation with exercise alter carnitine profiles, biochemical markers of fat metabolism and serum leptin concentration in healthy women. The Journal of Nutrition, 133(1), 84–89.
- Croze, M. L., & Soulage, C. O. (2013). Potential role and therapeutic interests of myo-inositol in metabolic diseases. Biochimie, 95(10), 1811-1827.
- Martinez, Y., Li, X., Liu, G., Bin, P., Yan, W., Mas, D., Valdivie, M., Hu, C.-A. A., Ren, W., & Yin, Y. (2017). The role of methionine on metabolism, oxidative stress, and diseases. Amino Acids, 49(12), 2091-2098.
- Murakami, S. (2015). Role of taurine in the pathogenesis of obesity. Molecular Nutrition and Food Research, 59(7).
- Brown, J. E., & Rice-Evans, C. A. (2009). Luteolin-rich artichoke extract protects low density lipoprotein from oxidation In vitro. Journal of Free Radical Research, 29(3), 247-255.
- Garcia-Carrasco, B., Fernandez-Dacosta, R., Davalos, A., Ordovas, J. M., & Rodriguez-Casado, A. (2015). In vitro hypolipidemic and antioxidant effects of leaf and root extracts of Taraxacum Officinale. Medical Sciences, 3, 38-54.
- Lorizola, I. M., Furlan, C. P. B., Portovedo, M., Milanski, M., Botelho, P. B., Bezerra, R. M. N., Sumere, B. R., Rostagno, M. A., & Capitani, C. D. (2018). Beet stalks and leaves (Beta vulgaris L.) protect against high-fat diet-induced oxidative damage in the liver in mice. Nutrients, 10, 872-888.
- Tung, Y.-C., Chang, W.-T., Li, S., Wu, J.-C., Badmeav, V., Ho, C.-T., & Pan, M.-H. (2018). Citrus peel extracts attenuated obesity and modulated gut microbiota in mice with high-fat diet-induced obesity. Food & Function (6).
- Choi, R.-Y., Nam, S.-J., Lee, H.-I., Lee, J., Leutou, A. S., Ham, J. R., Lee, & M.-K. (2019). Gentiopicroside isolated from Gentiana scabra Bge. Inhibits adipogenesis in 3T3-L1 cells and reduces body weight in diet-induced obese mice. Bioorganic and Medicinal Chemistry Letters, 29(14), 1699-1704.